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New controlled release systems produced by self-assembly of biopolymers and colloidal particles at fluid-fluid interfaces
Although the structure of cross-linking molecules mainly determines the structural organization of actin filaments and with that the static elastic properties of the cytoskeleton, it is largely unknown how the biochemical characteristics of transiently cross-linking proteins (actin-binding proteins (ABPs)) affect the viscoelasticity of actin networks. In this study, we show that the macroscopic network response of reconstituted actin networks can be traced back to the microscopic interaction potential of an individual actin/ABP bond. The viscoelastic response of cross-linked actin networks is set by the cross-linker off-rate, the binding energy, and the characteristic bond length of individual actin/ABP interactions. [hide]
Scientific Board
Andreas Bausch
TU Munich, Germany ►
Peter Fischer
ETH Zurich, Switzerland ►
Anne-Marie Hermansson
SIK, Sweden ►
Martin Kroger
ETH Zurich, Germany/Switzerland ►
Erik van der Linden
Wageningen UR, The Netherlands ►
Niklas Loren
SIK, Sweden ►
Leonard Sagis
Wageningen UR, The Netherlands ►
Erich Windhab
ETH Zurich, Switzerland ►
Klaas-Jan Zuidam
Unilever, The Netherlands ►
Scientific Stuff
Manuela Duxenneuner
ETH Zurich, Switzerland ►
Sophia Fransson
SIK, Sweden ►
Nam-Phuong Humblet-Hua
Wageningen UR, The Netherlands ►
Joeska Husny
ETH Zurich, Australia/Switzerland ►
Orit Peleg
ETH Zurich, Israel/Switzerland ►
Cyrille Vezy
TU Munich, Germany ►
Varvara Mitropoulos
ETH Zurich, Switzerland ►
Associated Scientists
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SY Tee, AR Bausch, PA Janmey,
The mechanical cell
CURRENT BIOLOGY 19 (2009) R745 ►Selected conferences (co-)organized by project members
8th World Congress on Computational Mechanics WCCM8 2008
30 June - 5 July 2007, Venice, Italy ►13 May 2025
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