Contributions
matching >Nowak.C<
Follow the blue link(s) below for abstracts and full text pdfs 
.
Author index ►
Most cited recent articles ►
Articles for free download ►
Search conferences ►
Johannes Nowak, Christoph Nowak, Stefan Odenbach
Consequences of sheep blood used as diluting agent for the magnetoviscous effect in biocompatible ferrofluids
Appl. Rheol. 25:5 (2015) 53250 (8 pages)
►
Magnetic nanoparticles suspended in suitable carrier liquids can be adopted for use in biomedicine. For this to be achieved,
the biocompatibility of these ferrofluids needs to be ascertained. In cancer treatment, potential applications currently under
investigation include, e.g. drug targeting by using magnetic fields and the destruction of diseased cells by applying alternating
magnetic fields, which cause heating of magnetic nanoparticles. To enable the use of ferrofluids in the actual biomedical
context, detailed knowledge of the flow characteristics is essential to ensure safe treatment. From ferrofluids used in the
engineering context, a rise of viscosity when a magnetic field is applied - the magnetoviscous effect - is well known. This
effect, which leads to an increased viscosity and profound alteration of a fluid's rheological behaviour, has also been demonstrated
for biocompatible ferrofluids used in the aforementioned applications. In biomedical applications, ferrofluids will be
diluted in the blood stream. Therefore, the interaction between whole blood and the ferrofluid has to be investigated. This is
the focus of the current experimental study, which makes use of two different ferrofluids diluted in sheep blood to gain a
deeper understanding of the fluid mixtures primarily regarding the relative change in viscosity if an external magnetic field
is applied. The results demonstrate a strong interaction between blood cells and structures formed by the magnetic nanoparticles
and show a high deviation of results compared to ferrofluids diluted in water. These findings have to be taken into
account for future research and applications of similar biocompatible fluids to guarantee safe and effective use in living
organisms.
► Cite this publication as follows:
Nowak J, Nowak C, Odenbach S: Consequences of sheep blood used as diluting agent for the magnetoviscous effect in biocompatible ferrofluids, Appl. Rheol. 25 (2015) 53250.
© Applied Rheology 2024
